Growth of Malignant Non-CNS Tumors Alters Brain Metabolome

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منابع مشابه

Growth of Malignant Non-CNS Tumors Alters Brain Metabolome

Cancer survivors experience numerous treatment side effects that negatively affect their quality of life. Cognitive side effects are especially insidious, as they affect memory, cognition, and learning. Neurocognitive deficits occur prior to cancer treatment, arising even before cancer diagnosis, and we refer to them as "tumor brain." Metabolomics is a new area of research that focuses on metab...

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PATTERN OF MALIGNANT TUMORS IN KERMAN PROVINCE

From March 1980 to March 1989 a total number of 2254 (7.6%) new malignant cases from Kerman province were diagnosed by examination of surgical specimens, blood films and bone marrow smears. The crude relative frequency of cancers was studied and compared with other areas of Iran. Gastric (11.36%) and urinary bladder (7.01 %) carcinomas were significantly more common in Kerman province than...

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Malignant Brain Tumors in Childhood

Although most brain tumors are sporadic, a number of pediatric brain tumor presentations are associated with recognized genetic syndromes. About 15–20% of children with neurofibromatosis (NF1) present with CNS neoplasms, usually gliomas of the optic pathways or low-grade tumors of the diencephalon, cerebral hemispheres, or posterior fossa (2). Low-grade gliomas associated with NF1 may be less a...

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Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice

A wide array of central nervous system complications, neurological deficits, and cognitive impairments occur and persist as a result of systemic cancer and cancer treatments. This condition is known as chemo brain and it affects over half of cancer survivors. Recent studies reported that cognitive impairments manifest before chemotherapy and are much broader than chemo brain alone, thereby addi...

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F-fluorothymidine kinetics of malignant brain tumors

Purpose F-labeled deoxy-fluorothymidine (FLT), a marker of cellular proliferation, has been used in PET tumor imaging. Here, the FLT kinetics of malignant brain tumors were investigated. Methods Seven patients with high-grade tumors and two patients with metastases had 12 studies. After 1.5 MBq/kg F-FLT had been administered intravenously, dynamic PET studies were acquired for 75 min. Images we...

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ژورنال

عنوان ژورنال: Frontiers in Genetics

سال: 2018

ISSN: 1664-8021

DOI: 10.3389/fgene.2018.00041